John B. O'Brien
- Title: John B. O'Brien
- Popularity: 0.844
- Known For: Directing
- Birthday: 1884-12-13
- Place of Birth: Roanoke, Virginia, USA
- Homepage:
- Also Known As: J.B. O'Brien, Jack G. O'Brien, Jack O'Brien, John D. O'Brien, John O'Brien, Ryan Sherwood